Old Crow Medicine Show celebrates two decades of “Wagon Wheel,” the song they turned into a folk anthem, kicking off their Tiny Desk concert with its unmistakable ramblin’ energy. The band’s high-octane blend of roots music shines through with “O Cumberland River” and “Wolfman of the Ozarks,” featuring train-like harmonica riffs and a jaw harp duet. They close with “One Drop,” a gospel-inspired call for unity, reminding us all why their music spans generations.
